高兴华

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高兴华,女19848月生,2012年赴美国Drexel University留学2年,2014年博士毕业于中国药科大学,现为中国药科大学药物科学研究院副研究员,硕士生导师,博士生导师。在国际重要学术期刊如PNASTheranosticsoncogene等发表SCI论文23篇,其中第一作者或通讯作者14篇,累计影响因子65分。PNAS文章被评为“高被引论文”,Theranostics文章被“热心肠日报微信公众号”追踪报道。担任GliaOxidative Medicine and Cellular Longevity等杂志的审稿人。先后主持国家自然科学基金面上项目1项,青年项目1项,江苏省自然科学基金青年项目1项,中国博士后科学基金面上项目1项。

研究方向:

主要研究方向为肿瘤药理,聚焦肿瘤免疫、免疫细胞代谢探索结肠炎、结肠癌等的病理机制,进行抗肿瘤药物研究与开发。同时探讨抑郁等不良情绪对炎症、癌症发生发展的促进作用及机制。

代表性论文:

1.      Wang Y,#  Quan F#, Cao Q, Lin Y, Xue C, Bi B, Cui X, Yang H, Yang Y, Birnbaumerd L, Li X*, Gao X*. Quercetin alleviates acute kidney injury by inhibiting ferroptosisJournal of Advanced Research.2021 Feb; 28:231-243.(corresponding author, IF: 6.992)

2.      Cao Q#, Gao X#, Lin Y, Yue C, Wang Y, Quan F, Zhang Z, Liu X, Lu Y, Zhan Y, Yang H, Li X, Qin D, Birnbaumer L, Hao K*, Yang Y*. Thymopentin ameliorates dextran sulfate sodium-induced colitis by triggering the production of IL-22 in both innate and adaptive lymphocytesTheranostics. 2019 Oct 12; 9 (25): 7490-7505. (Co-first author, IF: 8.579).

3.      Gao X#, Cao QH#, Cheng Y#, Zhao DD, Wang Z, Yang HB, Wu QJ, You LJ, Wang Y, Lin YT, Li XJ, Wang Y, Bian J-S, Sun DD, Kong LY, Birnbaumerd L*, Yang Y*Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response.Proc Natl Acad Sci U S A. 2018 Mar 27; 115(13):E2960-E2969. (IF: 9.580)

4.      Cheng Y#, Gao XH#, Li XJ#, Cao QH, Zhao DD, Zhou JR, Wu HX, Wang Y, You LJ, Yang HB, He YL, Li YR, Bian JS, Zhu QY, Birnbaumer L*, Yang Y*Depression promotes prostate cancer invasion and metastasis via a sympathetic-cAMP-FAK signaling pathway.Oncogene. 2018 May; 37(22):2953-2966. (Co-first author, IF: 6.634)

5.      Mao J, Liu S, Ai M, Wang Z, Wang D, Li X, Hu K, Gao X*, Yang Y*. A novel melittin nano-liposome exerted excellent anti-hepatocellular carcinoma efficacy with better biological safetyJ Hematol Oncol. 2017 Mar 20; 10(1):71. (co-corresponding author, IF 6.35)

6.      Gao XXia JMunoz FMManners MTPan RMeucci ODai YHu HSTIMs and Orai1 regulate cytokine production in spinal astrocytes.J Neuroinflammation2016 May 31; 13(1):126. ( IF 5.1020)

7.      Gao X, Gao R, Tian YZ, McGonigle P, Barrett JE, Dai Y*, Hu H*. A store-operated calcium channel inhibitor attenuates collagen-induced arthritis.Br J Pharmacol. 2015 Jun; 172(12):2991-3002. ( IF 5.2589)

联系方式:

邮箱:gaoxinghua@cpu.edu.cn

手机:13770537546

通信地址:南京市江宁区龙眠大道639号,中国药科大学安评中心,邮编211198