周晓辉

发布者： 陶书阳 浏览次数： 1695

一般情况

 

姓名：周晓辉

性别：男

学科专业：1.药理学；2.临床药学.

职称：副教授；主治医师

最高学历：医学博士

电子邮箱：zhxh@cpu.edu.cn

 

学习经历

 

1989～1994年：中国医科大学医学院，医学学士；

1997～2000年：辽宁中医药大学附属第一医院，医学硕士；

2000～2003年：上海中医药大学附属龙华医院，医学博士；

2012～2013年：密歇根大学(美国)医学院外科系免疫治疗研究室,访问学者.

 

工作经历

 

1994～2004年：沈阳医学院附属中心医院心胸外科，住院医师、主治医师、讲师；

2004～2006年：浙江大学药学院，药理学博士后；

2007年～至今：中国药科大学临床药学教研室，副教授；

东南大学附属中大医院、南京水西门医院，主治医师.

 

研究兴趣与方向

 

    1. 药理学：

      ①自身免疫与泌尿系统病变：Ⅲ型前列腺炎（CP/CPPS）、前列腺癌的发病机制、靶点发现、临床诊断与药物治疗的临床新策略研究；

      ②心血管药理：心脏综合诊疗平台—主动性液压心室贴附支持给药/监测系统（ASD）的作用机制、器械开发与临床新策略研究；

    2. 临床药学：临床药物治疗的转化医学研究.

       

      近年来承担主要课题

       

  1. 主持国家自然科学基金面上项目二项；

  2. 主持南京市领军型科技人才引进计划项目一项.

     

    学术任职

    1.   中华中医药学会中药实验药理分会委员；

    2.   中华中医药学会外科疮疡专业委员会委员.

     

    近五年内代表论文

  3. Liu Z, Naveed M, Baig M, Mikrani R, Li C, Saeed M, Zhang Q, Farooq M A, Zubair H M, Xiaohui Z (Corresponding author). Therapeutic approach for global myocardial injury using bone marrow-derived mesenchymal stem cells by cardiac support device in rats [J]. Biomed Microdevices, 2021, 23(1): 5.

  4. Mikrani R, Li C, Naveed M, Li C, Baig M, Zhang Q, Wang Y, Peng J, Zhao L, Zhou X (Corresponding author). Pharmacokinetic Advantage of ASD Device Promote Drug Absorption through the Epicardium [J]. Pharm Res, 2020, 37(9): 173.

  5. Liu Y, Wazir J, Tang M, Ullah R, Chen Y, Chen T, Zhou X (Corresponding author). Experimental autoimmune prostatitis: different antigens induction and antigen-specific therapy [J]. International urology and nephrology, 2020,

  6. Liu Y, Tang M, Zhang Q, Li C, Lv R, Min H and Zhou X (Corresponding author). T2 Peptide Represents a Major Autoantigen Epitope in Experimental Autoimmune Prostatitis. Inflammation. 2020.

  7. Ullah R, Wazir J, Khan FU, Diallo MT, Ihsan AU, Mikrani R, Aquib M and Zhou X (Corresponding author). Factors Influencing the Delivery Efficiency of Cancer Nanomedicines. AAPS PharmSciTech. 2020;21:132.

  8. Ullah R, Wazir J, Hossain MA, Diallo MT, Khan FU, Ihsan AU and Zhou X (Corresponding author). A glimpse into the efficacy of alternative therapies in the management of benign prostatic hyperplasia. Wien Klin Wochenschr. 2020.

  9. Liu Z, Mikrani R, Zubair HM, Taleb A, Naveed M, Baig M, Zhang Q, Li C, Habib M, Cui X, Sembatya KR, Lei H and Zhou X (Corresponding author). Systemic and local delivery of mesenchymal stem cells for heart renovation: Challenges and innovations. Eur J Pharmacol. 2020;876:173049.

  10. Liu Y, Mikrani R, Xie D, Wazir J, Shrestha S, Ullah R, Baig M, Ahmed A, Srivastava PK, Thapa KB and Zhou X (Corresponding author). Chronic prostatitis/chronic pelvic pain syndrome and prostate cancer: study of immune cells and cytokines. Fundam Clin Pharmacol. 2020;34:160-172.

  11. Liu Y, Mikrani R, He Y, Faran Asraf Baig MM, Abbas M, Naveed M, Tang M, Zhang Q, Li C and Zhou X (Corresponding author). TRPM8 channels: A review of distribution and clinical role. Eur J Pharmacol. 2020:173312.

  12. Yasmeen S, Liao X, Khan F U, Ihsan A U, Li X, Li C, Chen D, Yu F, Wang Z, Sembatya K R, Mikrani R, Zhou X (Corresponding author). A novel approach to devise the therapy for ventricular fibrillation by epicardial delivery of lidocaine using active hydraulic ventricular attaching support system: An experimental study in rats [J]. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2019, 107(5): 1722-1731.

  13. Wazir J, Ullah R, Li S, Hossain M A, Diallo M T, Khan F U, Ihsan A U, Zhou X (Corresponding author). Efficacy of acupuncture in the treatment of chronic prostatitis-chronic pelvic pain syndrome: a review of the literature [J]. Int Urol Nephrol, 2019.

  14. Tang M, Ullah R, Wazir J, Khan F U, Ihsan A U, Cui X, Wang W, Hu M, Liu Y, Zhou X (Corresponding author). Effect of Oral T2 Antigen on Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Mice Model [J]. Inflammation, 2019.

  15. Mikrani R, Liang C, Naveed M, Kamboh A A, Abbas M, Chaurasiya B, Xue L, Xiaohui Z (Corresponding author). A cardiac troponin I study in a minimally invasive myocardial infarction canine model [J]. Journal of Applied Biomedicine, 2019, 17(1): 39-39.

  16. Li X, Mikrani R, Li C, Naveed M, Liu Z, Abbas M, Cheng Y, Han L, Wang Z, Zhou X (Corresponding author). An epicardial delivery of nitroglycerine by active hydraulic ventricular support drug delivery system improves cardiac function in a rat model [J]. Drug Deliv Transl Res, 2019.

  17. Hu M, Wazir J, Ullah R, Wang W, Cui X, Tang M, Zhou X (Corresponding author). Phytotherapy and physical therapy in the management of chronic prostatitis-chronic pelvic pain syndrome [J]. Int Urol Nephrol, 2019, 51(7): 1081-1088.

  18. F. U. Khan N W, A. U. Ihsan, P. Khongorzul1, J. Wazir, W. Gang, Y. Mengqi, L. Xiaoqian, L. Han and Zhou Xiaohui (Corresponding author). Analysis of the Qualities Matching New Classification of Clinical Pharmacist [J]. Indian Journal of Pharmaceutical Sciences, 2019, 81(1): 2-10.

  19. Cheng Y, Cao Y, Ihsan A U, Khan F U, Li X, Xie D, Cui X, Wang W, Liu Z, Li C, Ahmad K A, Sembatya K R, Mikrani R, Zhou X (Corresponding author). Novel Treatment of Experimental Autoimmune Prostatitis by Nanoparticle-Conjugated Autoantigen Peptide T2 [J]. Inflammation, 2019, 42(3): 1071-1081.

  20. Cao Y, Cheng Y, Ihsan A U, Khan F U, Xie D, Cui X, Wang W, Zhou X (Corresponding author). A nanoparticle-coupled T2 peptide induces immune tolerance and ameliorates chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in mice model [J]. Fundamental & Clinical Pharmacology, 2019, 33(3): 267-276.

  21. Wang W, Naveed M, Baig M, Abbas M, Xiaohui Z (Corresponding author). Experimental rodent models of chronic prostatitis and evaluation criteria [J]. Biomed Pharmacother, 2018, 108:1894-1901.

  22. Ihsan A U, Khan F U, Khongorzul P, Ahmad K A, Naveed M, Yasmeen S, Cao Y, Taleb A, Maiti R, Akhter F, Liao X, Li X, Cheng Y, Khan H U, Alam K, Zhou X (Corresponding author). Role of oxidative stress in pathology of chronic prostatitis/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress [J]. Biomed Pharmacother, 2018, 106(714-723.

  23. Yue S, Naveed M, Gang W, Chen D, Wang Z, Yu F, Zhou X (Corresponding author). Cardiac support device (ASD) delivers bone marrow stem cells repetitively to epicardium has promising curative effects in advanced heart failure [J]. Biomed Microdevices, 2018, 20(2): 40.

  24. Naveed M, Han L, Hasnat M, Baig M, Wang W, Mikrani R, Zhiwei L, Sembatya K R, Xie D, Zhou X (Corresponding author). Suppression of TGP on myocardial remodeling by regulating the NF-kappaB pathway [J]. Biomed Pharmacother, 2018, 108, 1460-1468.

  25. Naveed M, Mohammad I S, Xue L, Khan S, Gang W, Cao Y, Cheng Y, Cui X, DingDing C, Feng Y, Zhijie W, Xiaohui Z (Corresponding author). The promising future of ventricular restraint therapy for the management of end-stage heart failure [J]. Biomedicine & pharmacotherapy, 2018, 99:25-32.

  26. Naveed M, Han L, Khan G J, Yasmeen S, Mikrani R, Abbas M, Cunyu L, Xiaohui Z (Corresponding author). Cardio-supportive devices (VRD & DCC device) and patches for advanced heart failure: A review, summary of state of the art and future directions [J]. Biomedicine & pharmacotherapy, 2018, 102:41-54.

  27. Naveed M, BiBi J, Kamboh A A, Suheryani I, Kakar I, Fazlani S A, FangFang X, Kalhoro S A, Yunjuan L, Kakar M U, Abd El-Hack M E, Noreldin A E, Zhixiang S, LiXia C, XiaoHui Z (Corresponding author). Pharmacological values and therapeutic properties of black tea (Camellia sinensis): A comprehensive overview [J]. Biomedicine & pharmacotherapy, 2018, 100:521-531.

  28. Nawaz W, Khan F U, Khan M Z, Gang W, Yang M, Liao X, Zhang L, Ihsan A U, Khan A, Han L, Zhou X (Corresponding author). Exo-organoplasty interventions: A brief review of past, present and future directions for advance heart failure management [J]. Biomedicine & pharmacotherapy, 2017, 88:162-172.

  29. Naveed M, Wenhua L, Gang W, Mohammad I S, Abbas M, Liao X, Yang M, Zhang L, Liu X, Qi X, Chen Y, Jiadi L, Ye L, Zhijie W, Ding C D, Feng Y, Xiaohui Z (Corresponding author). A novel ventricular restraint device (ASD) repetitively deliver Salvia miltiorrhiza to epicardium have good curative effects in heart failure management [J]. Biomedicine & pharmacotherapy, 2017, 95:701-710.

  30. Naveed M, Hejazi V, Abbas M, Kamboh A A, Khan G J, Shumzaid M, Ahmad F, Babazadeh D, FangFang X, Modarresi-Ghazani F, WenHua L, XiaoHui Z (Corresponding author). Chlorogenic acid (CGA): A pharmacological review and call for further research [J]. Biomedicine & pharmacotherapy, 2017, 97:67-74.

  31. Khan F U, Ihsan A U, Nawaz W, Khan M Z, Yang M, Wang G, Liao X, Han L, Zhou X (Corresponding author). A novel mouse model of chronic prostatitis/chronic pelvic pain syndrome induced by immunization of special peptide fragment with aluminum hydroxide adjuvant [J]. Immunol Lett, 2017, 187:61-67.

  32. Khan F U, Ihsan A U, Khan H U, Jana R, Wazir J, Khongorzul P, Waqar M, Zhou X (Corresponding author). Comprehensive overview of prostatitis [J]. Biomedicine & pharmacotherapy, 2017, 94:1064-1076.

  33. Zhang L, Ihsan A U, Cao Y, Khan F U, Cheng Y, Han L, Zhou X (Corresponding author). An Immunogenic Peptide, T2 Induces Interstitial Cystitis/Painful Bladder Syndrome: an Autoimmune Mouse Model for Interstitial Cystitis/Painful Bladder Syndrome [J]. Inflammation, 2017, 40(6): 2033-2041.

  34. Ihsan A U, Khan F U, Nawaz W, Khan M Z, Yang M, Zhou X (Corresponding author). Establishment of a rat model of chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) induced by immunization with a novel peptide T2 [J]. Biomedicine & pharmacotherapy, 2017, 91:687-692.

  35. Zhang L, Ihsan A U, Cao Y, Cheng Y, Zhou X (Corresponding author). Establishment of experimental autoimmune prostatitis model by T2 peptide in aluminium hydroxide adjuvant [J]. Andrologia, 2017.

  36. Yang M Q, Ye L L, Liu X L, Qi X M, Lv J D, Wang G, Farhan U K, Waqas N, Chen D D, Han L, Zhou X H (Corresponding author). Gingerol activates noxious cold ion channel TRPA1 in gastrointestinal tract [J]. Chin J Nat Med, 2016, 14(6): 434-440.

 

主编教材

  1. 《临床药理学》. 南京: 江苏凤凰科学技术出版社, 2018年.

     

    参编教材

  2. 《临床医学概论（第2版）》（全国高等学校药学类专业第八轮规划教材）.北京:人民卫生出版社，2016年；

  3. 《临床药物治疗学（案例版，第2版）》（全国高等医药院校规划教材）.北京:科学出版社，2017年；

  4. 《临床药物治疗学（第4版）》（药学类专业用全国高等学校教材）.北京:人民卫生出版社，2016年；

  5. 《临床中药学（第1版）》（中药学专业用全国高等学校教材）.北京:人民卫生出版社，2012年；

  6. 《临床药物治疗学（第3版）》（药学类专业用全国高等学校教材）.北京:人民卫生出版社，2011年；

  7. 《临床药物治疗学（案例版，第1版）》（全国高等医药院校规划教材）.北京:科学出版社，2009年。