邢磊

邢磊,男,博士,副教授,硕士研究生导师。2005年毕业于河南大学药学院药物制剂专业,2005~2008年在河南大学药学院攻读药剂学硕士学位,其中2006.7~2008.5期间在军事医学科学院金义光课题组从事自组装药物传递系统的研究;2008年考入上海交通大学化学化工学院,师从车顺爱教授,研究方向为pH响应性配位聚合物用于药物传递的研究,主要参与《国家973项目--纳米结构材料的程序化组装》和《重大新型药物开发项目》。20129月加入中国药科大学药学院药剂系从事教学科研工作。目前已在SCI期刊上发表较高水平论文26篇,总被引354次,其中他引 323次。以第一或共第一作者发表SCI论文17篇,累计影响因子近106。主持和参与的国家自然科学基金9项,江苏省自然基金4项,主持国重优秀青年人才基金1项。

研究方向:药用高分子材料与靶向释药系统;基于配位键的药物递送系统;聚合物药物递送系统

近期发表的文章:

1. Xing L, Lyu JY, Yang Y, Cui PF, Gu LQ, Qiao JB, He YJ, Zhang TQ, Sun M, Lu JJ, Xu X*, Liu Y*, Jiang HL*. pH-Responsive de-PEGylated nanoparticles based on triphenylphosphine–quercetin self-assemblies for mitochondria-targeted cancer therapy. Chem. Commun. 2017, 53(62): 8790-8793. (†equal contribution)

2. Luo CQ, Xing L, Cui PF, Qiao JB, He YJ, Chen BA, Jin L*, and Jiang HL*. curcumin-coordinated nanoparticles with improved stability for reactive oxygen species-responsive drug delivery in lung cancer therapy. Int. J Nanomed. 2017, 12: 855-869. (†equal contribution)

3. Zhang M, Xing L, Ke H, He YJ, Cui PF, Zhu Y, Jiang G, Qiao JB, Lu N, Chen H*, Jiang HL*. MnO2-Based Nanoplatform Serves as Drug Vehicle and MRI Contrast Agent for Cancer Theranostics. ACS Appl. Mater. & Inter. 2017, 9(13): 11337-11344. (†equal contribution)

4. He YJ, Xing L, Cui PF, Zhang JL, Zhu Y, Qiao JB, Lyu JY, Zhang M, Luo CQ, Zhou YX, Lu N*, Jiang HL*. Transferrin-inspired vehicles based on pH-responsive coordination bond to combat multidrug-resistant breast cancer. Biomaterials, 2017, 113: 266-278. (†equal contribution)

5. Wang FZ,Xing L,Tang ZH,Lu JJ,Cui PF,Qiao JB,Jiang L,Jiang HL*,Zong L*. Codelivery of Doxorubicin and shAkt1 by Poly(ethylenimine)-Glycyrrhetinic Acid Nanoparticles To Induce Autophagy-Mediated Liver Cancer Combination Therapy. Mol Pharm.2016,13(4):1298-1307. (†equal contribution)

6. Zhang BF†, Xing L†, Cui PF, Wang FZ, Xie RL, Zhang JL, Zhang M, He YJ, Lyu JY, Qiao JB, Chen BA, Jiang HL*. Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine. Biomaterials. 2015, 61: 178-189. (†equal contribution)

7. Su Z†, Xing L†, Chen Y, Xu Y, Yang F, Zhang C, Ping Q, Xiao Y*. Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas. Mol. Pharm. 2014, 11(6): 1823-1834. (†equal contribution)

8. Zheng H., Xing L, Cao Y, and Che S*, Coordination bonding based pH-responsive drug delivery systems, Coordin. Chem. Rev. 2013, 257: 1933-1944.

9. Xing L, Zheng H, Cao Y, Che S*, Coordination Polymer Coated Mesoporous Silica Nanoparticles for pH-Responsive Drug Release, Adv. Mater. 2012. 24: 6433-6437.

10.  Xing L, Cao Y, Che S*, Synthesis of Core-Shell Coordination Polymer Nanoparticles (CPNs) for pH-responsive Controlled Drug Release, Chem. Commun. 2012. 48: 5995-5997.

11. Xing L, Zheng H, Che S*, A pH-responsive Cleavage Route Based On a Metal-Organic Coordination Bonding, Chem. Eur. J. 2011, 17: 7271-7275.

联系方式

(1)手机:13675198929

(2)E-mailxinglei6xl@163.com