冯锋

冯锋,教授、博士生导师,中国药科大学理学院院长。

主要经历

20139月任中国药科大学理学院院长;

20125月任中国药科大学现代教育技术中心主任;

20095月任中国药科大学教务处副处长;

20051月美国University of California, Irvine访问学者;

20035月任中国药科大学中药学院党委副书记;

200112月获中国药科大学药物化学博士学位;

19947月获中国药科大学药物化学硕士学位并留校任教;

研究方向

天然药物活性成分提取分离、结构修饰及体内分析。

学术兼职与获奖

中国中药新技术专业委员会常务理事

江苏省“333高层次人才培养工程第三层次

江苏省教育厅青蓝工程中青年学术带头人培养对象

江苏省科技进步二等奖(天然产物为基础的抗肿瘤新药的应用基础研究与开发)

研究成果

主持自然科学基金面上项目靶向神经血管单元研究钩藤散防治血管性痴呆的物质基础和基于转运体的配伍机制(项目号81373956

主持十二五重大科技专项中药一类抗呼吸道病毒新药黄芩素片的临床前研究(项目号2011ZX09102-009-05

主持江苏省三药基金项目黄芩素片的研制(项目号0606038

作为主要完成人参与多项国家和省部级课题,包括自然科学基金重点项目(30830116),自然科学基金面上项目(81274064, 30701032)以及十五国家重大科技专项(2003AA2Z3267, 2004AA2Z3A10)十一五重大科技专项(2009zx09102-032, 2009zx09103-094)等。

近年在本课题相关领域共申请公开发明专利7项,已授权发明专利4项,发表研究论文60余篇,其中在Journal of Pharmaceutical and Biomedical Analysis, Journal of Chromatography B, Journal of Separation Science, Journal of Ethnopharmacology, Cancer Letters, Toxicology, Journal of Asian Natural Products ResearchSCI期刊发表文章30余篇。

 

近三年发表的主要文章:

1)             FENG Feng, XU Xi-Yu, LIU Fu-Lei, LIU Wen-Yuan, XIE Ning. Triterpenoid saponins from Patrinia scabra. Chinese Journal of Natural Medicines. 2014,12(1):43-46.

2)             Tian Guo, Yuanyuan Shi, Li Zheng, Feng Feng, Feng Zheng, Wenyuan Liu*. Rapid and simultaneous determination of sulfonate ester genotoxic impurities in drug substance by liquid chromatography coupled to tandem mass spectrometry: comparison of different ionisation modes. Journal of Chromatography A (2014), 1355(73-79).

3)             Yanan Gai, Han Chen, ChunYong Wu, Feng Feng, YiXiang Wang, WenYuan Liu, SuiLou Wang. Analysis of the traditional medicine YiGan San by the fragmentation patterns of cadambine indole alkaloids using HPLC coupled with high-resolution MS. J. Sep. Sci, 2013, 36:3723-3732. 

4)             Lin Li, Yanyang Zhao, Wenyuan Liu, Feng Feng, Ning Xie. HPLC with quadrupole TOF-MS and chemometrics analysis for the characterization of Folium Turpiniae from different regions. J. Sep. Sci, 2013, 36:2552-2561. 

5)             Shuanglu Xie, Yuanyuan Shi, Yixiang Wang, Chunyong Wu, Wenyuan Liu, Feng Feng, Ning Xie. Systematic identification and quantification of tetracyclic monoterpenoid oxindole alkaloids in Uncaria rhynchophylla and their fragmentations in Q-TOF-MS spectra. Journal of Pharmaceutical and Biomedical Analysis2013, 81-82:56-64

6)             Li Lei, Liu Wenyuan, Feng Feng, Wu Chunyong, Xie Ning. Synthesis and in vitro cytotoxicity evaluation of baicalein amino acid derivatives. Chinese Journal of Natural Medicines. 2013, 11 (3):284-288.

7)             Yatao Shi, Chunyong Wu, Yanhua Chen, Wenyuan Liu, Feng Feng, Ning Xie. Comparative analysis of three Callicarpa herbs using high performance liquid chromatography with diode array detector and electrospray ionization-trap mass spectrometry method. Journal of Pharmaceutical and Biomedical Analysis. 2013, 75:239– 247

8)             Ying Xia, Chunyong Wu, Wenyuan Liu, Feng Feng, Zhiyu Li. A novel process related impurity and forced degradation study of synthetic wogonin: Development of a liquid chromatographic method for purity control. Journal of Pharmaceutical and Biomedical Analysis2012, 71:168- 172.

9)             Cui-Min Yan, Bei-Bei Zhang, Wen-Yuan Liu, Feng Feng, Yong-Gang Zhao, Hui Du. Rapid determination of sixteen sulfonylurea herbicides in surface water by solid phase extraction cleanup and ultra-high-pressure liquid chromatography coupled with tandem mass spectrometry. Journal of Chromatography B, 87920113484-3489.

10)          Wenyuan Liu, Ainan Zhou, Feng Feng, Huibin Zhang, Jinpei Zhou, Wenlong Huang. Qualitative and quantitative studies on impurities in G004, a potential hypoglycaemic agent, using liquid chromatography, nuclear magnetic resonance and mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2011, 56627– 632

 

联系方式:

南京市鼓楼区童家巷24,中国药科大学天然药物化学教研室(210009)

南京市江宁区龙眠大道639号 中国药科大学理学院(211198)

Tel025-86185180E-mailfengfeng@cpu.edu.cn